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Template
In general terms, it is a mold or pattern that can be copied or its shape reproduced. When used with reference to molecular dimensions, it is a macromolecular mold or pattern for the synthesis of another macromolecule. For example, during 2003 Angela Belcher, Daniel Solis, and Chuanbin Mao genetically engineered a pencil-shaped bacteriophage known as M13 so that it expressed & incorporated into its capsid a peptide which causes and controls nucleation/condensation-onto-it of specific nanometer-size (conductor) particles. After those (conductor) nanoparticles thereby become deposited in very specific order onto the bacteriophage pencil-shaped "template", exposure to very high temperature removes the bacteriophage; leaving a solid NANOWIRE. For example, during 2003, Susan Lindquist:
For example, during 2002, William A. Drucker and Chang-Hyun Jang were able to utilize the enzyme acetylcholinesterase as a "template" to create a precisely-structured strip 70-nanometers wide deposited onto a prepared gold surface. After first coating the the gold surface with a carboxylic acid (film), they were able to adhere onto it a film of acetylcholinesterase; then by scratching-away a strip via utilization of an atomic force microscope tip (stylus), they were able to to lay-down a 70-nanometer wide strip (onto the gold) of thiocholine cleaved from acetylcholine-containing solution.
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The term "TEMPLATE" also appears in the definition(s) of the following term(s): DNA Ligase  Polyribosome (polysome)  Primer (DNA)  RNA Polymerase  Transcription   |
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