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The substitution of a purine for a pyramidine, or of a pyramidine for a purine (at a specific site, within a given nucleotide in a molecule of DNA). That substitution generally results from a mutation in an organism's DNA.
NUCLEOTIDE,  DEOXYRIBONUCLEIC ACID (DNA),  SINGLE-NUCLEOTIDE POLYMORPHISMS (SNPs),  MUTATION,  BASE SUBSTITUTION


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