Hedgehog Signaling Pathway
A signaling pathway which is critical to development (i.e., of many embryonic organisms into adult organisms). Via this pathway, hedgehog proteins direct/control tissue differentiation (into various organs, limbs, etc.) as the embryo develops into an adult body. Hedgehog proteins also control left-right asymmetry of the developing body. When the body reaches adult form, the hedgehog signaling pathway shuts down (epigenetically). Research indicates that if the hedgehog signaling pathway is (wrongly) "turned on" in an adult body, it can promote development of some cancers.
Cancer ,   Cell ,   Cell Differentiation ,   Protein ,   Signal Transduction ,   Signaling ,   Differentiation ,   Hedgehog Proteins ,   Pathway ,   Signaling Protein ,   Epigenetic ,   Cell Motility


The term "Hedgehog Signaling Pathway" also appears in the definition(s) of the following term(s):
Hh
  Smoothened
 
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