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Mutation
From the Latin term mutare, meaning "to change". Any change that alters the sequence of the nucleotide bases in the genetic material (DNA) of an organism or cell; with alteration occurring either by displacement, addition, deletion, cross-linking, or other destruction. The mutation alteration to the DNA sequence would alter its meaning, that is, its ability to produce the normal amount or normal kind of protein, or normal miRNA gene; so the (organism or cell) is itself altered. Such an altered organism is called a mutant. For example, during the eighteenth century, one orange tree in Brazil was discovered to be producing seedless oranges; as a result of a naturally-ocurring mutation in its DNA. If that particular mutation was of a single nucleotide in that orange tree's DNA (e.g., caused by ultraviolet radiation striking it), then it was a point mutation. Since all commercial seedless orange trees existing today are direct descendants of that one Brazilian tree, that mutation was a stable mutation.
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